"There were a lot of people just standing around trying to see what was going on. Because of the time, a lot were coming out of work."
The road was closed for about three hours.
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A spokesman for Northumbria Police said: "Officers are particularly keen to speak to any motorists or pedestrians who were in the Ormonde Street or the roads from the Barnes roundabout area in the time before the collision and who may have seen a blue Volvo S60 or a turquoise Vauxhall Corsa driving in the area."
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l Anyone with information is asked to telephone Northumbria Police on 101.
Traffic was diverted while collision investigators examined the scene between Cleveland Road and Ormonde Street.
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A consultant from Sunderland Royal Hospital treated the girl on board the air ambulance after it took off from Barnes Park in Prada Bag Inside
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The teenager is in intensive care in the hospital.
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Officers say they are also keen to trace witnesses who saw a turquoise Vauxhall Corsa in the area which they believe was involved in the incident.
A 35 year old businessman who was leaving work and saw the aftermath of the accident said: "I'm not surprised something like this has happened. Cars charge through those lights because they don't stay on green for very long."
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Sunderland, flying to the RVI.
Ms Parker, of Grangetown, said: "There were two wheels left in the middle of the road and the police were speaking to a man sitting on a blue car.
Police closed off part of the road at 5.30pm on Tuesday as paramedics treated the girl, believed to be from the Barnes area, before she was flown by air ambulance to Newcastle's Royal Victoria Infirmary.
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Police are now appealing for anyone in the area at the time to come forward.
Witnesses described how the girl was hit by a blue Volvo and left lying in the middle of Ormonde Street, halfway between traffic lights and a pedestrian crossing. Catharine Parker, 43, was on a shuttle bus which was diverted away.
Man charged after teenager seriously injured in crash
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